Dow Jones Futures Rise, Nasdaq 100 Falls as Iran Threatens to Target Undersea Cables

U.S. stock futures swung between gains and losses on Tuesday as the Dow Jones index rose, while the S&P 500 and Nasdaq 100 indices fell, following Monday’s mixed close.

Iranian Foreign Minister Abbas Araghchi accused French President Emmanuel Macron of trying to deflect responsibility for France’s unrest after previously expressing support for U.S. military action against Iran.

Reuters reported that French authorities imposed curfews in parts of Paris, Lille, and Nice on Monday after a weekend of riots and looting linked to nationwide anti-government protests.

Separately, Iran’s IRGC spokesperson Hossein Mohebi threatened to target undersea communication cables in the Strait of Hormuz, saying that “all of the world’s internet and commercial data depend on them,” Al Jazeera reported.

Tuesday features highly anticipated third-quarter earnings reports from Netflix Inc. (NASDAQ: NFLX), General Motors Co. (NYSE: GM), GE Aerospace (NYSE: GE), 3M Co. (NYSE: MMM), and RTX Corporation (NYSE: RTX).

Meanwhile, the 10-year Treasury bond yielded 5.11%, and the 2-year Treasury bond yielded 4.76% at the last check. The CME Group’s FedWatch tool projections show markets pricing in an 82.8% likelihood of the Federal Reserve keeping interest rates unchanged after its October meeting. Benzinga reports.

🧪 Rapport Therapeutics Announces Positive Topline Results from Its Phase 2 Trial of RAP-219. Stock Up in Pre-Market

The trial met the primary and secondary endpoints with statistically significant placebo-adjusted improvements at Week 3 in the YMRS total score (3.1 points; p=0.045) and CGI-BP Severity of Mania score (0.4 points; p=0.024).

RAP-219–treated patients had a 15.4-point mean reduction in YMRS total score from baseline at Week 3.

All 11 items measured by the YMRS improved numerically compared to placebo at Week 3, with improvements in irritability, thought content, disruptive-aggressive behavior, and sexual interest reaching nominal significance.

RAP-219 was well tolerated; all treatment-emergent adverse events during the treatment period were mild or moderate.

The company will host a conference call today at 8:00 a.m. ET. Yahoo Finance reports.

🏗️ CoreWeave Stock Sinks to 52-Week Low as Wall Street's AI Debt Fears Deepen
CoreWeave Inc. (NASDAQ: CRWV) stock fell more than 3% in Tuesday’s premarket trading as concerns over the AI cloud provider’s rising borrowing costs and heavy debt continued to weigh on investor sentiment.

The decline came amid broader market weakness, with Nasdaq futures down 0.37% and S&P 500 futures slipping 0.04%.

Despite strong demand for AI computing infrastructure and renewed optimism from Wall Street analysts, CoreWeave has struggled to rebound from a sharp selloff. The stock is down nearly 15% year to date. Benzinga reports.

🧬 Oracle Joins Forces with AstraZeneca to Put AI to Work in Drug Research
Oracle Corp. (NYSE: ORCL) announced on Tuesday a nonbinding agreement with AstraZeneca Plc (NYSE: AZN) to explore using artificial intelligence and real-world data to improve clinical-trial recruitment and connect research findings with everyday care.

The companies plan to pair AstraZeneca’s scientific and therapeutic expertise with Oracle’s health data, cloud, analytics, and clinical workflow capabilities.

Their goals include identifying eligible patients sooner, expanding access to trials, and accelerating evidence generation.

Initial areas of focus could include oncology; cardiovascular, renal, and metabolic diseases; respiratory and immunology; and rare diseases. Benzinga reports.

🏢 Why 3M Shares Are Trading Higher
Shares of 3M Co. (NYSE: MMM) rose sharply in pre-market trading.

Amazon.com Inc. (NASDAQ: AMZN) expanded its data center partnership with 3M and received a warrant to buy about $521.4 million worth of 3M stock, with vesting tied to the hyperscaler’s purchases of data center products.

3M Company will also release its third-quarter earnings before the opening bell on Tuesday, Oct. 20.

3M shares jumped 4.4% to $169.20 in pre-market. Benzinga reports.

💾 Micron and Other Chip Stocks Spring Back to Life After Bruising Selloff
After a painful selloff spanning nearly two weeks, the chip sector is on the mend.

Nvidia’s stock (NVDA) closed up 1.4% Monday, while rival Advanced Micro Devices’ stock (AMD) finished up about 1.7%. Shares of Micron Technology (MU) and Intel (INTC), which have both been major beneficiaries of artificial intelligence demand so far this year, climbed about 3% and 2.4%, respectively. Sandisk’s stock (SNDK) also rebounded Monday, finishing up 5.5%. The iShares Semiconductor ETF (SOXX) was up 1.7%.

Shares of neocloud company Nebius Group (NBIS), which delivers cloud services focused on AI workloads, bounced 2.9% higher.

The chip sector slid over the previous eight sessions as investors questioned the sustainability of AI spending growth. Investors took issue with reports of financial progress at privately held AI companies OpenAI and Anthropic. MarketWatch reports.

(All pricing and percent gains are based on Early Pre-Market from 4:00 AM to 7:00 AM ET). Stock Analysis reports.

1) SAIQ: WISeSat.Space Holdings Corp.
Total gain: +52.49%

2) WORX: SCWorx Corp.
Total gain: +39.55%

3) AIXI: Xiao-I Corporation
Total gain: +23.86%

4) GIXI: Gix Internet Ltd.
Total gain: +11.00%

5) RAPP: Rapport Therapeutics, Inc.
Total gain: +10.49%

The closing price of the top three market percent gainers trading near or above $2 on Oct 19.

(All pricing and percent gains are based on regular market trading hours from 9:30 AM to 4:00 PM ET). Stock Analysis reports.

1) SLN: Silence Therapeutics plc
Total gain: +125.58%

The company announced its entry into a definitive agreement to acquire Silence Therapeutics plc (Nasdaq: SLN), a global clinical-stage biotechnology company headquartered in London, UK, focused on pioneering the design and development of siRNA (short interfering RNA) therapies in areas of high unmet need. BusinessWire reports.

2) WORX: SCWorx Corp.
Total gain: +94.20%

The announced that it has entered into a new agreement with an independent, community-owned healthcare system serving the New Mexico, Arizona, Colorado and Utah. Under the agreement, SCWorx will provide its healthcare supply chain data management services to support the health system’s efforts to improve the accuracy, completeness and usability of its healthcare product data. GlobeNewswire reports.

3) XHG: XChange TEC.INC
Total gain: +60.00%

The stock appeared to be moving on no notable news.

(Estimate and Actual numbers represent Earnings Per Share in US Dollars)

NFLX

Netflix

Q3 2026

After Market Close

Estimate: 0.820

Actual: N/A

SPCX

SpaceX

Q3 2026

After Market Close

Estimate: 0.160

Actual: N/A

PEGA

Pegasystems

Q3 2026

After Market Close

Estimate: 0.430

Actual: N/A

Time (ET) / Report / Period

• 8:30 AM / Housing Starts / Sep
• 10:00 AM / Pending Home Sales Idx, M/M% / Sep

“Markets can remain irrational longer than you can remain solvent.”

- John Maynard Keynes
Sourced in: Top 200 Investing Quotes [2026] - DigitalDefynd

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